What are my current HIV treatment goals?

Two important goals of treatment for people living with HIV are to:

• Reduce your viral load (the amount of HIV in your blood) to as low as possible
• Increase your CD4 cell count

Keeping your viral load as low as possible and increasing your CD4 count may reduce the risk of some serious problems that can happen when your immune system is weaker.

What other HIV medicines will I be taking?

EDURANT^® must be taken in combination with other HIV medicines. Your healthcare professional will work with you to find the right combination of HIV medicines.

How do I take EDURANT^®?

• Take EDURANT^® every day exactly as your healthcare professional tells you to.
• Take EDURANT^® 1 time each day with a meal. A protein drink alone does not replace a meal.
• Do not change your dose or stop taking EDURANT^® without first talking with your healthcare professional. Stay under the care of your healthcare professional during treatment with EDURANT^®.
• Do not miss a dose of EDURANT^®.
• If you take an H₂-receptor antagonist (famotidine, cimetidine, nizatidine, or ranitidine), you should take these medicines at least 12 hours before or at least 4 hours after you take EDURANT^®.
• If you take antacids, or other products that contain aluminum, calcium carbonate, or magnesium hydroxide, you should take these medicines at least 2 hours before or at least 4 hours after you take EDURANT^®.
• If you miss a dose of EDURANT^® within 12 hours of the time you usually take it, take your dose of EDURANT^® with a meal as soon as possible. Then, take your next dose of EDURANT^® at the regularly scheduled time. If you miss a dose of EDURANT^® by more than 12 hours of the time you usually take it, wait and then take the next dose of EDURANT^® at the regularly scheduled time.
• Do not take more than your prescribed dose to make up for a missed dose.
• If you take too much EDURANT^®, call your healthcare professional or go to the nearest hospital emergency room right away.
• When your supply of EDURANT^® starts to run low, get more from your healthcare professional or pharmacy. It is important not to run out of EDURANT^®. The amount of HIV in your blood may increase if the medicine is stopped even for a short time.
• When your healthcare professional prescribes use of EDURANT^® with oral VOCABRIA (cabotegravir):
  • Take EDURANT^® and oral VOCABRIA (cabotegravir) once a day at approximately the same time with a meal.
  • You will receive treatment with EDURANT^® tablets in combination with oral VOCABRIA (cabotegravir) tablets for one month (at least 28 days) before you receive the long-acting medicine called CABENUVA (cabotegravir; rilpivirine extended-release injectable suspensions) for the first time. This will allow your healthcare professional to assess how well you tolerate these medicines.
  • Your final dose of EDURANT^® and oral VOCABRIA should be taken on the same day you receive your first CABENUVA injections.
  • If you miss or plan to miss a scheduled monthly or every 2 months injection of CABENUVA by more than 7 days, call your healthcare professional right away to discuss your treatment options.

Do not stop taking EDURANT^® or any other medicines without first talking to your healthcare professional. For more information, ask your doctor or pharmacist.

What if I want to become pregnant?

If you are pregnant or plan to become pregnant, it is not known if EDURANT^® will harm your unborn baby. Tell your healthcare professional if you become pregnant during treatment with EDURANT^®.

There is a pregnancy registry for women who take EDURANT^® during pregnancy. The purpose of this registry is to collect information about the health of you and your baby. Talk with your healthcare professional about how you can take part in this registry.

What if I am breastfeeding?

Before taking EDURANT^®, tell your doctor if you:

• Are breastfeeding or plan to breastfeed. Do not breastfeed if you take EDURANT^®. You should not breastfeed if you have HIV-1 because of the risk of passing HIV-1 to your baby. It is not known if EDURANT^® passes into your breast milk. Talk with your healthcare professional about the best way to feed your baby during EDURANT^® treatment

How can I remember to take my medicine?

• Connect your pills with something you do every day. EDURANT^® must be taken with a meal, so plan to take it with breakfast, lunch, or dinner every day
• Keep your pills in a pillbox and carry them with you when you go out. This way, wherever you are, you’ll always have them handy
• Use computer reminders, telephone reminders, and watches, anything that trains you to remember. Forgetting is the most common reason for missing pills
• Place a reminder note near something you use every day—your refrigerator or television, for example. When you see your note, you’ll remember to take your medicine
• Talk to a member of your care team at your healthcare provider's office for support

Do not stop taking EDURANT^® or any other medicines without first talking to your healthcare professional.

Where can I get additional information?

Janssen CarePath

Janssen CarePath offers resources and support that may help you get started and stay on track with EDURANT^® treatment as prescribed by your doctor. Call a Janssen CarePath Care Coordinator at 1-866-836-0114, Monday-Friday 8:00 am to 8:00 pm ET or visit www.JanssenCarePath.com.

Janssen CarePath Savings Program for EDURANT^®

Eligible patients using commercial or private insurance can save on out-of-pocket costs for EDURANT^®. Eligible patients pay $0 per fill, up to a $7,500 maximum program benefit per calendar year. Patients using Medicare, Medicaid, or other government-funded programs to pay for their medications are not eligible to participate. Terms expire at the end of each calendar year and may change. There is no income requirement. See full eligibility requirements at JanssenCarePathSavings.com or call Janssen CarePath at: 1-866-836-0114.

Janssen Therapeutics Medical Information

Janssen Therapeutics Medical Information is committed to providing current, accurate, and unbiased medical information about our products. If you have a question regarding our products, please call us at 1‐800‐JANSSEN(1‐800‐526‐7736). If you need to report a possible adverse event or product quality complaint, please call us immediately at 1‐800‐JANSSEN (1‐800‐526‐7736).